PELVIC LYMPH NODE DISSECTION IN RADICAL PROSTATECTOMY: A STUDY OF 5,048 CASES.
Introduction
Pelvic lymph node dissection (PLND) represents the most accurate and reliable staging procedure for the detection of lymph node (LN) invasion in prostate cancer. Which candidates to select for this procedure and PLND’s extent are still points of discussion
Objectives
To present the data of a large series of radical prostatectomy-associated-PLND.
Methods
Data from 5,048 radical prostatectomy (RP) were studied. The number of cases in which PLND was performed, the number of LNs dissected and associations to patient’s age, Gleason biopsy score and PSA were analyzed.
Results
Patient’s mean age was 63.5 years-old; mean PSA was 9.49 ng/mL. PLND was not performed in 459 patients. When performed, was always bilateral; in 87 cases PLND was referred as “extended”. Number of LNs dissected ranged from 1-27 (2.95 ± 2.71). In 376 cases, no LNs were identified, in spite of use of LN-revealing solution. Metastasis were found in less than 1% of the cases; in these patients mean PSA was 35.55 ng/mL, and Gleason biopsy’s score ranged from 6 to 9.
Conclusion
The results indicates that, in the great majority of cases there is a lack of standardization regarding RP-associated-PLND and that PLND is usually performed in
lymph node dissection
cancer
prostate
ONCOLOGIA
Paulo Guilherme O Salles, Walter Luiz Ribeiro Cabral, André Lopes Salazar, Renato B. Corradi Fonseca, Andy Petroianu
